Engineered Particles for Chemical Communication

ERC (European Research Council)HORIZON-ERCID: 101052997
EC Contribution
€24,992
Consortium Size
2 orgs
Start Year
2022
Summary

This project aims to the development of communication at the nanoscale and to advance in the understanding of how abiotic micro/nanoparticles can communicate between them and how micro/nanoparticles can communicate with living systems. In this context, an approach for establishing communication at the nanometric level is to mimic how nature communicates. Chemical or molecular communication, based on transmitting and receiving information by means of molecules (chemical messengers) is one of the communication forms used by living organisms. Moreover, many swarm systems found in nature communicate by modifying the environment using a concept called stigmergy. The advantages of nanoparticles that communicate each to another are immediately obvious; they constitute the basis of a dynamically interacting network eventually resulting in certain autonomy of the system. If we would be able to raise the bases for communication between micro/nanoparticles and between micro/nanoparticles and cells, the potential future applications in the biomedical field, environmental research and industry technology are almost unlimited. The project will establish firm handholds for the use of nanoparticles able to communicate from one to another and with cells in different applications. The project will trace, optimise and adapt all single steps from the idea to its implementation into applicable final systems with the aim of targeting issues that are difficult to address with conventional single particles. The project is divided into three WPs. The first work package (WP1) will create the basic elements for chemical communication. In a more complex situation, WP2 will use the tools of WP1 to develop systems able to establish communication between nanoparticles and living systems. Finally, WP3 will generate nano-systems integrating gated nanoparticles and up-to-date electronics to develop new communication structures.

Consortium (2)

Project Results (12)

Source: CORDIS, the EU research results database.

Publications (11)
ACS applied materials & interfaces
ACS Applied Materials and Interfaces· 2025DOI
Blanca Escriche-Navarro; Eva Garrido; Sandra Clara-Trujillo; Anna Labernadie; Félix Sancenon; Alba García-Fernández; Ramón Martínez-Máñez
Natural antimicrobials synergistically coupled with nanomotors: An innovative strategy for biofilm eradication
Food Research International· 2025DOI
Serena Medaglia, Andrea Escudero, Ángela Morellá-Aucejo, Francisco J. Hicke, Miguel Reyes-Torres, Lucia Marin-Ferrandis, Pedro Amorós, María Dolores Marcos, Andrea Bernardos, Paula Díez, Ramón Martínez-Máñez
SARS-COV-2 viral RNA detection through oligonucleotide-capped nanoporous anodic alumina supports.
Sensors and Actuators Reports· 2025DOI
Alba López-Palacios, María Nieves Aranda, Isabel Caballos, Andy Hernández-Montoto, Eva Calabuig, María Dolores Gómez-Ruiz, María Ángeles Tormo-Mas, Javier Pemán, Félix Sancenón, Ramón Martínez-Máñez, Elena Aznar, Estela Climent
A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells
Acta Biomaterialia· 2024DOI
Escriche-Navarro, B., Garrido, E., Sancenón, F., García-Fernández, A., Martínez-Máñez, R.
Chemical Communication between Giant Vesicles and Gated Nanoparticles for Strip-Based Sensing
Nano Letters· 2024DOI
Ventura-Cobos, J., Climent, E., Martínez-Máñez, R., Llopis-Lorente, A.
Chemical Strategies for the Detection and Elimination of Senescent Cells
Accounts of Chemical Research· 2024DOI
García-Fleitas, J., García-Fernández, A., Martí-Centelles, V., Sancenón, F., Bernardos, A., Martínez-Máñez, R.
Models of Chemical Communication for Micro/Nanoparticles
Accounts of Chemical Research· 2024DOI
Ventura, J., Llopis-Lorente, A., Abdelmohsen, L.K.E.A., van Hest, J.C.M., Martínez-Máñez, R.
Spatiotemporal Communication in Artificial Cell Consortia for Dynamic Control of DNA Nanostructures
ACS Central Science· 2024DOI
Llopis-Lorente, A., Shao, J., Ventura, J., Buddingh′, B.C., Martinez-Manez, R., van Hest, J.C.M., Abdelmohsen, L.K.E.A.
Engineering nanoparticle communication in living systems by stigmergy: An application to enhance antitumor therapy in triple-negative breast cancer
Nano Today· 2023DOI
Estepa-Fernández, A., García-Fernández, A., Lérida-Viso, A., Morellá-Aucejo, Á., Esteve-Moreno, J.J., Blandez, J.F., Alfonso, M., Candela-Noguera, V., Vivo-Llorca, G., Sancenon-Galarza, F., Orzáez, M., Martínez-Máñez, R.
Ficin–Cyclodextrin-Based Docking Nanoarchitectonics of Self-Propelled Nanomotors for Bacterial Biofilm Eradication
Chemistry of Materials· 2023DOI
Žiemytė, M., Escudero, A., Díez, P., Ferrer, M.D., Murguía, J.R., Martí-Centelles, V., Mira, A., Martínez-Máñez, R.
Quorum sensing communication between lipid-based artificial cells
Chemical Communications, 59(5), 579 - 582. Royal Society of Chemistry· 2023DOI
Antoni Llopis-Lorente; Bastiaan C. Buddingh'; R. Martínez-Máñez; Jan C. M. van Hest; Loai K. E. Abdelmohsen
Other Results (1)
Periodic Reporting for period 1 - EDISON (Engineered Particles for Chemical Communication)