Twinning for intensified enzymatic processes for production of prebiotic-containing functional food and bioactive cosmetics

Widening ParticipationHORIZON-CSAID: 101060130
EC Contribution
€14,667
Consortium Size
4 orgs
Start Year
2022
Summary

The general objective of the project is to advance the research and innovation capacity of the Faculty of Technology and Metallurgy (FTM) in the area of prebiotics technology by collaboration with leading institutions with complementary expertise able to implement substantial improvement of the research staff profile, project management and administration skills. The consortium includes Maastricht University and Radboud university medical center contributing with the expertise in analysis of human microbiota, which provides determination of the activity of prospective gut and skin prebiotics, and Spanish National Research Council contributing with the expertise in protein engineering, which enables improvement of catalytic properties of enzymes applied in production of prebiotics. In addition to transferring knowledge within these two areas expertise, specific objectives are also to strengthen management capacities of the FTM, to unleash potential of young scientists and to form network of scientific community and potential industrial partners. Joint research is designed to result with joint scientific publication, which will increase research profile and attractiveness of the FTM and provide wider scientific impact by dissemination in accordance with open science concept. Additionally, wider economic, technological and societal impact will be facilitated through establishment of the Center of Scientific Excellence for Prebiotics and two innovative prebiotic technologies developed to technology readiness level 6. Still, motives behind formation of the consortium goes beyond goals of this project because long-term sustainable cooperation between four institutions is envisioned. All members of the consortium foresee increased demand for innovative prebiotic technologies, for which the consortium with such a high level of interdisciplinarity is needed.

Consortium (4)

Project Results (32)

Source: CORDIS, the EU research results database.

Publications (21)
Agro-Waste Valorization: Extraction and Characterization of a Polyphenol-Rich Fraction from Sunflower Meal
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Lara Denić, Teodora Zakić, Milica Veljković, Milica Simović, Katarina Banjanac, Anja Petrov Ivanković, Ana Vukoičić, Dejan Bezbradica
Amino-lignin microspheres loaded with Fe3O4 nanoparticles as support for xylanase immobilization: application in prebiotics synthesis
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Katarina Banjanac, Jelena Gržetić, Ana Popović, Milica Veljković, Milica Simović, Aleksandar Marinković, Dejan Bezbradica
Assessment of Enzymatically Derived Blackcurrant Extract as Cosmetic Ingredient—Antioxidant Properties Determination and In Vitro Diffusion Study
Pharmaceutics· 2025DOI
Anja Petrov Ivanković, Marija Ćorović, Ana Milivojević, Stevan Blagojević, Aleksandra Radulović, Rada Pjanović, Dejan Bezbradica
Developing and improving enzyme-driven technologies to synthesise emerging prebiotics
Green Chemistry· 2025DOI
Noelia Losada-Garcia, Milica Simović, Marija Ćorović, Ana Milivojević, Nikola Nikačević, Cesar Mateo, Dejan Bezbradica, Jose M. Palomo
Enzymatic oligomerization of phloridzin in betaine-based deep eutectic solvent
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Ana Vukoičić, Anja Petrov Ivanković, Milica Veljković, Marija Ćorović, Katarina Banjanac, Ana Milivojević, Dejan Bezbradica
Evaluation of amino-modified nanocellulose carrier for immobilization of xylanase and application in xylo-oligosaccharide synthesis
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Katarina Katić, Katarina Banjanac, Milica Veljković, Ana Vukoičić, Anja Petrov Ivanković, Milica Simović, Dejan Bezbradica
Influence of avocado seed extract obtained by ultrasonic extraction on rebalancing skin staphylococci
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Ana Milivojević, Ana Vukoičić, Kaja Kupnik, Anja Petrov Ivanković, Marija Ćorović, Mateja Primožič, Dejan Bezbradica
Integrated extraction and enzymatic hydrolysis for emerging prebiotic production from agro-industrial waste
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Aleksandra Tomić, Milica Veljković, Katarina Banjanac, Dejan Bezbradica, Nikola Nikačević
Investigating the Effect of Enzymatically-Derived Blackcurrant Extract on Skin Staphylococci Using an In Vitro Human Stratum Corneum Model
Pharmaceutics· 2025DOI
Marija Ćorović, Anja Petrov Ivanković, Ana Milivojević, Klaus Pfeffer, Bernhard Homey, Patrick A. M. Jansen, Patrick L. J. M. Zeeuwen, Ellen H. van den Bogaard, Dejan Bezbradica
Optimized production of oligosaccharides using arabinogalactan-rich fraction isolated from blackcurrant pomace as raw material
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Marija Ćorović, Anja Petrov Ivanković, Paula Lopes Revenga, Antonia Montilla, Ana Milivojević, Milica Veljković, Javier Moreno, Dejan Bezbradica
Polyphenol-rich strawberry extract as potential modulator of skin microbiota
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Anja Petrov Ivanković, Marija Ćorović, Ana Milivojević, Ana Vukoičić, Katarina Banjanac, Milica Simović, Milica Veljković, Dejan Bezbradica2
Production of polyphenol-rich fraction from rapeseed meal as a potential source of antioxidants and prebiotics
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Teodora Zakić, Lara Denić, Milica Veljković, Milica Simović, Katarina Banjanac, Ljiljana Stojadinović-Tolić, Svetlana Grujić, Dejan Bezbradica2
Separation of xylo-oligosaccharides using ultra- and nanofiltration membranes and investigation of their prebiotic effect
International Conference Biobased Future: Green bioprocessing for innovative bioactive products, June 16-18, 2025, Belgrade, Serbia, 2025· 2025
Milica Veljković, Marija Đukić, Milica Simović, Katarina Banjanac, Ana Vukoičić, Anja Petrov Ivanković, Dejan Bezbradica
Artificial Manganese Metalloenzymes with Laccase-like Activity: Design, Synthesis, and Characterization
ACS Applied Bio Materials· 2024DOI
Carla Garcia-Sanz, Alicia Andreu, Mirosława Pawlyta, Ana Vukoičić, Ana Milivojević, Blanca de las Rivas, Dejan Bezbradica, Jose M. Palomo
Berries Pomace Valorization: From Waste to Potent Antioxidants and Emerging Skin Prebiotics
International Journal of Fruit Science· 2024DOI
Anja Petrov Ivanković, Marija Ćorović, Ana Milivojević, Milica Simović, Katarina Banjanac, Milica Veljković, Dejan Bezbradica
Removal of raffinose and stachyose from soy-based beverages using soluble and immobilized MelA α-D-galactosidase from Lactiplantibacillus plantarum WCFS1
LWT· 2024DOI
Leandro Alves dos Santos, Paloma Delgado-Fernández, Ana Muñoz-Labrador, Diego Martin-Gutierrez, Evelyn C. Romero, Franzory Cuaran, Andrea Garcia-Alvarez, Elena García-Calvo, Blanca de las Rivas, Ro
Sunflower Meal Valorization through Enzyme-Aided Fractionation and the Production of Emerging Prebiotics
Foods· 2024DOI
Simović, Milica; Banjanac, Katarina; Veljković, Milica; Nikolić, Valentina; López-Revenga, Paula; Mantilla, Antonia; Moreno, Francisco Javier; Bezbradica, Dejan
Tailoring the natural rare sugars D-tagatose and L-sorbose to produce novel functional carbohydrates
npj Science of Food· 2024DOI
Oswaldo Hernandez-Hernandez; Carlos Sabater; Inés Calvete-Torre; Elisa G. Doyagüez; Ana M. Muñoz-Labrador; Cristina Julio-Gonzalez; Blanca de las Rivas; Rosario Muñoz; Lorena Ruiz; Abelardo Margol
Valorisation of Blackcurrant Pomace by Extraction of Pectin-Rich Fractions: Structural Characterization and Evaluation as Multifunctional Cosmetic Ingredient
Polymers· 2024DOI
Ćorović, Marija; Petrov Ivanković, Anja; Milivojević, Ana; Veljković, Milica; Simović, Milica; López-Revenga, Paula; Montilla, Antonia; Moreno, Francisco Javier; Bezbradica, Dejan
Enzymatic Glycosylation Strategies in the Production of Bioactive Compounds
Catalysts· 2023DOI
Alicia Andreu, Marija Ćorović, Carla Garcia-Sanz, A. Sofia Santos, Ana Milivojević, Clara Ortega-Nieto, Cesar Mateo, Dejan Bezbradica, Jose M. Palomo
In vitro evaluation of enzymatically derived blackcurrant extract as prebiotic cosmetic ingredient: extraction conditions optimization and effect on cutaneous microbiota representatives
Chemical and Biological Technologies in Agriculture· 2023DOI
Petrov Ivanković A., Milivojević A., Ćorović M., Simović M., Banjanac K., Janssen P., Vukoičić A., van den Bogaard E., Bezbradica D.
Deliverables (11)