Organ-on-a-Chip Focused Strategic Partnership

Widening ParticipationHORIZON-CSAID: 101079473
EC Contribution
€14,929
Consortium Size
4 orgs
Start Year
2022
Summary

OrChESTRA project aims to build solid and productive links between ODTÜ MEMS (Turkey) and three internationally-leading counterparts; TU/e (The Netherlands), IMEC (Belgium), and UFR (Germany), in order to strengthen scientific and research capacity of BioMEMS Research Unit of ODTÜ MEMS by raising the research profile of its staff and broadening its recognition as a centre of excellence in the field of microfluidics, biosensors, and particularly organ-on-a-chip systems. With the four twinning partners in place, ODTÜ MEMS aims to acquire the expertise needed not only to fill the identified gaps regarding knowledge, capacity, and networking, but also to join leading networks of excellence in microfluidics, biosensors, and organ-on-a-chip based research areas as an equal partner. The consortium expects to expand the R&D capabilities of the partners, to attract and provide scientific personnel via the OrChESTRA to the thematic focus of microfluidics, biosensors, and organ-on-a-chip systems, contributing to critical mass for the widespread application of such promising systems. Empowering the partnering organisations will result in knowledge transfer, joint publications and future research projects. The consortium is strongly committed to further develop this partnership with a long-term sustainable horizon of cooperation beyond the project.Consequently, OrChESTRA project aims to promote new opportunities for the consortium members via development of productive and sustainable links among them for higher levels of excellence in the field of microfluidics, biosensors, and organ-on-a-chip platforms, with a major focus on enhancing the range of competences of the coordinator. Objectives dedicated to achieve this goal:1. Raising the research profile of ODTÜ MEMS and its researchers2. Enhancing institutional capacity of ODTÜ MEMS3. Excellence in the wider impact for the ecosystem and beyond4. Integration into European networks of excellence

Consortium (4)

Project Results (28)

Source: CORDIS, the EU research results database.

Publications (7)
Convergence of nanotechnology and CRISPR-based diagnostics
Nature Nanotechnology· 2025DOI
Midori Johnston, Schan Dissanayake-Perera, James J. Collins, Molly M. Stevens, Can Dincer
Electrochemical Sensors for Rapid Cardiovascular Disease Diagnostics
ACS Sensors· 2025DOI
Vildan Sanko, H. Cumhur Tekin
MIP-on-the-flow: Molecularly imprinted polymers in microfluidic sensing systems
TrAC Trends in Analytical Chemistry· 2025DOI
Meltem Okan, Vildan Sanko, Ender Yıldırım, H. Cumhur Tekin, Haluk Külah
Applied body-fluid analysis by wearable devices
Nature· 2024DOI
Noé Brasier; Joseph Wang; Wei Gao; Juliane R. Sempionatto; Can Dincer; H. Ceren Ates; Firat Güder; Selin Olenik; Ivo Schauwecker; Dietmar Schaffarczyk; Effy Vayena; Nicole Ritz; Maja Weisser; Sally Mtenga; Roozbeh Ghaffari; John A. Rogers; Jörg Goldhahn
Cas13d-mediated gene knockdown in CAR T cells: towards off-the-shelf cancer treatment
Signal Transduction and Targeted Therapy· 2024DOI
Midori Johnston; Nadine Urban; Can Dincer
Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity
Microchimica Acta· 2024DOI
Pelin Saglam-Metiner, Ender Yildirim, Can Dincer, Onur Basak, Ozlem Yesil-Celiktas
ICU patient-on-a-chip emulating orchestration of mast cells and cerebral organoids in neuroinflammation
Communications Biology· 2024DOI
Pelin Saglam-Metiner; Sena Yanasik; Yusuf Caglar Odabasi; Jennifer Modamio; Moritz Negwer; Cigir Biray-Avci; Ayse Guler; Ali Erturk; Ender Yildirim; Ozlem Yesil-Celiktas
Deliverables (20)
Other Results (1)
Periodic Reporting for period 1 - OrChESTRA (Organ-on-a-Chip Focused Strategic Partnership)