Risk AssessmenT InnOvatioN for low-risk pesticides

Food, Bioeconomy & Natural ResourcesHORIZON-RIAID: 101084163
EC Contribution
€69,947
Consortium Size
22 orgs
Start Year
2022
Summary

Low risk pesticides (LRP) including (i) plant extracts (ii) semiochemicals like pheromones and allelochemicals, (iii) microbial pesticides, are gaining ground in the global market, as substitutes of synthetic pesticides. In addition, new microbial solutions (phages, protists, microbial consortia) and ds-RNA pesticides are emerging, low-risk solutions expect to reach the market in coming years. Despite on-going regulatory efforts by the European Commission, we are still lacking a concrete risk assessment (RA) scheme relevant to LRPs, a point which blocks LRPs reaching the EU market. RATION timely comes to address these regulatory constraints and aims to develop a novel RA scheme, supported by the necessary guidance on methods and tools, tailored to the specific characteristics of established and emerging LRP solutions. This main goal will be achieved through a series of interrelated WPs aiming (i) to map the current status of LRPs in Europe and identify main regulatory constraints (WP1). In this quest it will be supported by a stakeholders forum composed of all relevant actors (industry, regulators, academics, famers, general public); (ii) to develop and validate, through a proof-of-concept exercise, innovative RA (and associated tools) for microbials (WP2), plant extracts, semiochemicals, pheromones (WP3) and, ds-RNA (WP4); and from there (iii) build a harmonized RA for all LRP and determine its socioeconomic impact (WP5), (iv) to effectively communicate and disseminate the new RA knowledge and its associated tools developed by RATION to relevant actors ensuring sustainability beyond project duration (WP6). RATION will benchmark EU regulatory science, uplift blockers holding back LRP uptake by the EU market and motivate research innovation in plant protection. To achieve these goals 22 partners from academia, industry and regulatory bodies, representing 10 member states and 2 non-EU member states, will join forces in a multi-sectoral and multi-disciplinary effort.

Consortium (22)

Project Results (21)

Source: CORDIS, the EU research results database.

Publications (11)
Benefits and challenges of upcoming microbial plant protection applications sustaining planetary health
iScience· 2025DOI
Kalliope Κ. Papadopoulou, Antonis Chatzinotas, Belén Guijarro Diaz-Otero, Günter Brader, Dimitrios G. Karpouzas, Monica Garces Ruiz, José Luis Alonso Prados, Stéphane Declerck, Loukia M. Kellari, Angela Sessitsch
Chalcones—Features, Identification Techniques, Attributes, and Application in Agriculture
Molecules· 2025DOI
Magdalena Dziągwa-Becker, Marta Oleszek, Sylwia Zielińska, Wiesław Oleszek
Development and efficacy of dsRNA pesticides targeting the Colorado potato beetle with enhanced stability via chitosan formulations
Pesticide Biochemistry and Physiology· 2025DOI
Mohammad Vatanparast, Khalid Amari
Dissipation and Adsorption Behavior Together with Antioxidant Activity of Pinocembrin Dihydrochalcone
Applied Sciences· 2025DOI
Magdalena Dziągwa-Becker, Marta Oleszek, Aleksandra Ukalska-Jaruga, Mariusz Kucharski, Weronika Kozłowska, Marcel Białas, Sylwia Zielińska
dsRNA analyzer: a bioinformatic tool for targeted dsRNA design in arthropods
EU OPEN RESERARCH REPOSITORY· 2025DOI
Andronis, Christos; Ioannidis, Panagiotis; Vontas, John
DsRNA-based pesticides: Considerations for efficiency and risk assessment
Chemosphere· 2025DOI
Athanasios Dalakouras, Venetia Koidou, Kalliope Papadopoulou
dsRNAEngineer: a web-based tool of comprehensive dsRNA design for pest control
Trends in Biotechnology· 2025DOI
Yang Chen, Yufei Shi, Ziguo Wang, Xin An, Siyu Wei, Christos Andronis, John Vontas, Jin-Jun Wang, Jinzhi Niu
Environmental fate and ecotoxicological parameters differentiate between low-risk pesticides, candidates for substitution and conventional chemicals
Environmental Sciences Europe· 2025DOI
Tsaloumi, Swaine, Tsaboula, Vryzas, Karpouzas
Exogenous Application of dsRNA in Plant Protection: Efficiency, Safety Concerns and Risk Assessment
International Journal of Molecular Sciences· 2024DOI
Mohammad Vatanparast, Lisa Merkel, Khalid Amari
Harnessing the plant microbiome for sustainable crop production
Nature Reviews Microbiology· 2024DOI
Stéphane Compant, Fabricio Cassan, Tanja Kostić, Linda Johnson, Günter Brader, Friederike Trognitz, Angela Sessitsch
Is the Biopesticide from Tea Tree Oil an Effective and Low-Risk Alternative to Chemical Pesticides? A Critical Review
Molecules· 2024DOI
Magdalena Dziągwa-Becker; Marta Oleszek
Deliverables (9)
Other Results (1)
Periodic Reporting for period 1 - RATION (Risk AssessmenT InnOvatioN for low-risk pesticides)