Advanced epigenetics studies to increase the research and innovations capacity of the Roumen Tsanev Institute of Molecular Biology of the Bulgarian Academy of Sciences

HORIZON.4.1HORIZON-CSAID: 101086923
EC Contribution
€24,990
Consortium Size
1 orgs
▶Summary

The global objective of the Roumen Tsanev Institute of Molecular Biology is to develop its traditionally strong focus on epigenetics and chromatin biology towards a world-class level of research excellence. Our Institute has identified Prof. Stefan Dimitrov - a top level scientist and an internationally recognised expert in the field of epigenetics -as a prospective ERA Chair holder. We intend to achieve significant improvements in research and innovations capabilities of the IMB-BAS in the area of the Institute's long term specialisation, producing a clear impact on publication quality and newly acquired knowledge with translational potential. This should be achieved by:- Transfer of knowledge with a major focus on PhD students and young postdocs to provide for sustainable growth of IMB-BAS and reduce the ""brain drain""

Consortium (1)

🇧🇬 ROUMEN TSANEV INSTITUTE OF MOLECULAR BIOLOGY BULGARIAN ACADEMY OF SCIENCESBG
coordinator

Project Results (12)

Source: CORDIS, the EU research results database.

▶Publications (6)
Monogenic forms of inflammatory bowel disease: Genetic mechanisms, models, and clinical implications
Molecular Medicine· 2026
Amirhossein Ghorbanpour, Pejman Rohani, Shabnam Shahrokh, Georges Dimitrov, Mehdi Totonchi, Stefan Dimitrov
Identification of a novel DNA oxidative damage repair pathway, requiring the ubiquitination of the histone variant macroH2A1.1
BMC Biology· 2024DOI
Khalid Ouararhni, Flore Mietton, Jamal S. M. Sabir, Abdulkhaleg Ibrahim, Annie Molla, Raed S. Albheyri, Ali T. Zari, Ahmed Bahieldin, Hervé Menoni, Christian Bronner, Stefan Dimitrov, Ali Hamiche
Nucleic Acids Research
Nucleic Acids Research· 2024DOI
Edwige Belotti, Nicolas Lacoste, Arslan Iftikhar, Thomas Simonet, Christophe Papin, Alexis Osseni, Nathalie Streichenberger, Pierre-Olivier Mari, Emmanuelle Girard, Mohamed Graies, Giuseppina Giglia-Mari, Stefan Dimitrov, Ali Hamiche,Laurent Schaeffer
The CENP-A nucleosome: where and when it happens during the inner kinetochore’s assembly
Trends in Biochemical Sciences· 2024DOI
Seyit Kale, Ramachandran Boopathi, Edwige Belotti, Imtiaz Nisar Lone, Mohamed Graies, Maria Schröder, Maria Petrova, Christophe Papin, Jan Bednar, Iva Ugrinova, Ali Hamiche, Stefan Dimitrov
Molecular Mechanism of Nucleosome Recognition by the Pioneer Transcription Factor Sox
"Journal of Chemical Information and Modeling, 2023, 63 (12), pp.3839-3853. ⟨10.1021/acs.jcim.2c01520⟩"· 2023DOI
Burcu Ozden; Ramachandran Boopathi; Ayşe Berçin Barlas; Imtiaz N. Lone; Jan Bednar; Carlo Petosa; Seyit Kale; Ali Hamiche; Dimitar Angelov; Stefan Dimitrov; Ezgi Karaca
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1-4
FEBS Open BioDOI
Abed Alkarem Abu Alhaija; Imtiaz Nisar Lone; Esin Ozkuru Sekeroglu; Tugce Batur; Dimitar Angelov; Dimitrov Stefan; Ali Hamiche; Elif Nur Firat Karalar; Muhammed Erdem Ercan; Tamer Yagci; Hani Alotaibi; Muhammed Kasim Diril
▶Deliverables (5)
D1.1 - Handbook, outlining management structures and procedures
Documents, reports
D1.2 - Data management plan
Data Management Plan
D2.3 - Working principles and formation of the ERA Chair group
Documents, reports
D2.4 - ERA Chair group formation
Documents, reports
D6.1 - Plan of dissemination, exploitation and communication activities
Documents, reports
▶Other Results (1)
Periodic Reporting for period 1 - AEGIS-IMB (Advanced epigenetics studies to increase the research and innovations capacity of the Roumen Tsanev Institute of Molecular Biology of the Bulgarian Academy of Sciences)