Regional Center of Excellence at the Orbeli Institute of Physiology

Widening ParticipationHORIZON-CSAID: 101087403
EC Contribution
€24,150
Consortium Size
1 orgs
Start Year
2022
Summary

Through the Horizon Europe ERA Chairs action program, we aim to enhance the research environment in the Orbeli Institute of Physiology (IPH), a major biomedical academic entity established over 75 years ago in Yerevan. With the help of the Horizon Europe ERA Chair action program, we aim to modify the research and innovation landscape within the Orbeli Institute of Physiology (IPH), a major academic entity established over 75 years ago in Yerevan, Armenia. Under the direction of the proposed ERA Chair, a new scientific direction is to be developed and a number of key structural changes within IPH are to be implemented. These include 1) establishing a regional research center with a focus on tissue engineering, 2) educating a new generation of junior researchers in modern methods and approaches to collect and analyze data, 3) improving the institute's research compliance environment, including setting up committees on animal and human subjects, 4) institute-wide training in grant writing and management. In addition, to achieve long-term sustainability of IPH research efforts, the ERA Chair holder aims to establish collaborations with regional medical centers with an ultimate goal to help to manufacture bioscaffolds & implantable biomimetic tissues as well as to establish protocols for testing and culturing patient-derived pluripotent stem cells. In addition to being one of the most exciting scientific fields of the 21st Century, tissue engineering and regenerative medicine represent a true bridge between academia and medicine which brings scientific discoveries to the realm of everyday life. Horizon Europe ERA Chair grant can enable the IPH to build upon its existing scientific arsenal and resources to achieve regional leadership in the field of tissue engineering and regenerative medicine, becoming a driving force for strengthening Armenias science base in a variety of disciplines, ranging from biology, physics, chemistry, nanotechnology, and biomedical engineering.

Consortium (1)

Project Results (14)

Source: CORDIS, the EU research results database.

Publications (11)
4D hyperspectral imaging for intraoperative tissue classification
Medical Imaging 2025: Clinical and Biomedical Imaging· 2025DOI
Narek Chilingaryan, Fernando Villarruel, Tigran Soghomonyan, Varduhi Yeghiazaryan, Narine Sarvazyan
Bolus MPTP Injection in Aged Mice to Mimic Parkinson Disease: Effects of Low-Dose Antioxidant Treatment with Fullerene (C60) and Fullerenol (C60(OH)24)
Biomedicines· 2025DOI
Tatyana Strekalova, Alisa Burova, Anna Gorlova, Kirill Chaprov, Anastasia Khizeva, Joana E. Coelho, Evgeniy Svirin, Polina Novikova, Lia Ohanyan, Johannes J. M. P. de Munter, Naira Ayvazyan, Luisa V. Lopes, Aleksei Umriukhin, Gohar Arajyan, Harry W. M. Steinbusch
Changes in attachment and metabolic activity of rat neonatal cardiomyocytes and nonmyocytes caused by Macrovipera lebetina obtusa venom
Toxicology in Vitro· 2025DOI
Hovhannes Arestakesyan, Narine LeFevre, Nikki Posnack, Arni Sarian, Vahan Grigoryan, Naira Ayvazyan, Armen Voskanyan, Narine Sarvazyan, Zaruhi Karabekian
Combining 4D Hyperspectral Imaging With CNN for Nerve and Ligament Differentiation
2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)· 2025DOI
Naira Matosyan, Narek Chilingaryan, Narine Sarvazyan, Varduhi Yeghiazaryan
Comparative Analysis of Deep Learning Methods for Classification of Ablated Regions in Hyperspectral Images of Atrial Tissue
IEEE Access· 2025DOI
Yeva Gabrielyan, Arpi Hunanyan, Sona Bezirganyan, Lusine Davtyan, Ani Avetisyan, Narine Sarvazyan, Aram Butavyan, Varduhi Yeghiazaryan
Hematological and coagulation alterations and splenic response following Macrovipera lebetina obtusa envenomation: Evaluation of ovine-derived experimental antivenom
PLOS Neglected Tropical Diseases· 2025DOI
Gevorg Avagyan, Vardan Dabaghyan, Heghine Khachatryan, Ashot Aslanyan, Arsen Kishmiryan, Anna Karapetyan, Naira Ayvazyan
Macrovipera lebetinus obtusa Venom and Its Fractions Affect Human Dermal Microvascular Endothelial and Fibrosarcoma Cells
International Journal of Molecular Sciences· 2025DOI
Narine Ghazaryan, Lars Van Werven, Thomas Liepold, Olaf Jahn, Luis A. Pardo, Naira Ayvazyan
Spectral pixels as images: CNN-based pixel classification of 4D hyperspectral data for nerve and ligament differentiation
Medical Imaging 2025: Image Processing· 2025DOI
Naira Matosyan, Narek Chilingaryan, Narine Sarvazyan, Varduhi Yeghiazaryan
Surface Acoustic Waves-Based Molecular Recognition of a Collagen Receptor on Human Erythrocytes
International Journal of Molecular Sciences· 2025DOI
Gevorg Ghukasyan, Narine Ghazaryan, Michael Torosyan, Naira Movsisyan, Ashot Meltonyan, Naira Ayvazyan
Ultrastructural Remodeling of Cardiomyocytes in Postinfarction Myocardium of Rats in the Late Stages of the Disease
Cytometry Part A· 2025DOI
Sergei A. Fedotov, Andrei V. Stepanov, Galina A. Sakuta, Ivan S. Andreev, Marina S. Ivanova, Ekaterina V. Baidyuk
Histopathological changes of mice tissues in course of the envenomation by the Macrovipera lebetina obtusa venom and the neutralizing effect of the ovine-derived experimental antivenom
Toxicon· 2024DOI
Gevorg Avagyan, Hasmik Yeranosyan, Arsen Kishmiryan, Ruzanna Shushanyan, Arthur Melkonian, Naira M. Ayvazyan
Deliverables (2)
Demonstrators, pilots, prototypes
Demonstrators, pilots, prototypes
Other Results (1)
Periodic Reporting for period 1 - NAR-SAR-IPH (Regional Center of Excellence at the Orbeli Institute of Physiology)