Scaling Up secure Processing, Anonymization and generation of Health Data for EU cross border collaborative research and Innovation

HealthHORIZON-RIAID: 101095717
EC Contribution
€69,997
Consortium Size
19 orgs
Start Year
2023
Summary

The overall goal of the SECURED project is to scale up multiparty computation, data anonymization and synthetic data generation, by increasing efficiency and improving security, with a focus on private and unbiased artificial intelligence and data analytics, health-related data and data hubs, and cross-border cooperation. The project will address the limitations that are currently preventing the widespread use of secure multiparty computation and effective anonymization, namely: the limited practical capabilities of current cryptographic schemes for secure multi-party computation protocols, and their performance; the lack of well understood and standardized data anonymization methods for health data; the absence of dynamic and on demand services for generating synthetic data; the complex and ad-hoc nature of current federation protocols for machine learning and AI-based data analytics; the lack of support for health technology providers to implement privacy enhancing technologies, in particular SMEs.SECURED will tackle these challenges by focusing on scaling up privacy technologies via algorithmic improvements and implementation efficiency (HW and SW), as well as the generalization of primitives and definitions, with the aim of speeding up and facilitating privacy preserving data-driven tools and services for wellbeing, prevention, diagnosis, treatment and follow-up care. SECURED will also analyse the current ethical and legal challenges to data sharing, and is targeted at overcoming current limited adoption of advanced multi-party computation and data anonymization technologies by providing direct support to health technology SMEs through a funding call. To ensure relevance to real-world settings, SECURED will showcase the technologies developed in four health-related use cases provided by partner hospitals and health stakeholders, namely: real-time tumor classification; telemonitoring for children; synthetic data generation for education; access to genomic data.

Consortium (19)

Project Results (49)

Source: CORDIS, the EU research results database.

Publications (38)
Anonymising personal data under the data legislative acquis established by the Data Governance Act
Computer Law & Security Review· 2026DOI
Emanuela Podda, Daniela Spajic, Pierangela Samarati
HEALTH-DP: A Framework for Health Data De-Anonymization Risk Assessment and Mitigation with Differential Privacy.
12th International Conference on Information Systems Security and Privacy· 2026
Hamza Aguelal, Akasha Shafiq and Paolo Palmieri
<i>SynthVal</i> : A Framework for Validating Synthetic Medical Images
IEEE Access· 2025DOI
Dario Guidotti, Laura Pandolfo, Alberto Gutierrez-Torre, Omar Lopez-Rubio, Luca Pulina
A Knowledge-Driven Approach to Threat Validation and Security Reasoning in Modular Systems
IEEE Access· 2025DOI
Laura Pandolfo, Giorgio Corona, Dario Guidotti, Luca Pulina
Chapter 5 Transforming the secondary use of patient data in the European Health Data Space: A challenge for the patient’s right to medical confidentiality?
Computational and Structural Biotechnology Journal· 2025DOI
Spajić, Daniela
Data Altruism Consent: A Move Forward Towards the Creation of a European Health Data Space?
Data Science, Machine Intelligence, and Law· 2025DOI
Daniela Spajić
De-Anonymization of Health Data: A Survey of Practical Attacks, Vulnerabilities and Challenges
Proceedings of the 11th International Conference on Information Systems Security and Privacy· 2025DOI
Hamza Aguelal, Paolo Palmieri
Detect & Score: Privacy-Preserving Misbehavior Detection and Contribution Evaluation in Federated Learning
Proceedings of the International Workshop on Secure and Efficient Federated Learning· 2025DOI
Marvin Xhemrishi, Alexandre Graell i Amat, Balazs Pejo
ECG De-Anonymization: Real-World Risks and a Privacy-by-Design Mitigation Strategy
2025 IEEE 38th International Symposium on Computer-Based Medical Systems (CBMS)· 2025DOI
Hamza Aguelal, Paolo Palmieri
Efficient and Realistic Brain Simulation: A Review and Design Guide for Memristor‐Based Approaches
Advanced Materials Technologies· 2025DOI
Lennart Paul Liong Landsmeer; Muhammad Ali Siddiqi; Heba Abunahla; Mario Negrello; Said Hamdioui; Christos Strydis
Efficient implementation of the Hodgkin-Huxley potassium channel via a single volatile memristor
Frontiers in Neuroscience· 2025DOI
Lennart P. L. Landsmeer; Erbing Hua; Heba Abunahla; Muhammad Ali Siddiqi; Ryoichi Ishihara; Chris I. De Zeeuw; Said Hamdioui; Christos Strydis
FRIDA: Free-rider detection using privacy attacks
Journal of Information Security and Applications· 2025DOI
Pol G. Recasens, Ádám Horváth, Alberto Gutierrez-Torre, Jordi Torres, Josep Ll Berral, Balázs Pejó
Homeostatic bidirectional plasticity in upbound and downbound micromodules in a model of the olivocerebellar loop
PLOS Computational Biology· 2025DOI
Elías M. Fernández Santoro; Lennart P.L. Landsmeer; Said Hamdioui; Christos Strydis; Chris I. De Zeeuw; Aleksandra Badura; Mario Negrello
IEEE Access
IEEE Access· 2025DOI
Max C. W. Engelen; River Betting; Christos Strydis
In-Context Bias Propagation in LLM-Based Tabular Data Generation
International Conference on Machine Learning (ICML) 2025· 2025
Pol G. Recasens, Alberto Gutierrez-Torre, Jordi Torres, Josep Lluis Berral, Anisa Halimi, Kieran Fraser
SimHH: A Versatile, Multi-GPU Simulator for Extended Hodgkin-Huxley Networks
IEEE Access· 2025DOI
Max C. W. Engelen, River Betting, Christos Strydis
Synthetic data in medicine: Legal and ethical considerations for patient profiling
Computational and Structural Biotechnology Journal· 2025DOI
Nisevic, Maja; Milojevic, Dusko; Spajic, Daniela
Towards generalizable Federated Learning in medical imaging: A real-world case study on mammography data
Computational and Structural Biotechnology Journal· 2025DOI
Ioannis N. Tzortzis; Alberto Gutierrez-Torre; Stavros Sykiotis; Ferran Agulló; Nikolaos Bakalos; Anastasios Doulamis; Nikolaos Doulamis; Josep Ll. Berral
A Lightweight Architecture for Real-Time Neuronal-Spike Classification
CF '24: Proceedings of the 21st ACM International Conference on Computing Frontiers· 2024DOI
Siddiqi, M. A., Vrijenhoek, D., Landsmeer, L. P. L., van der Kleij, J., Gebregiorgis, A., Romano, V., Bishnoi, R., Hamdioui, S., & Strydis, C.
Annotated dataset for training deep learning models to detectastrocytes in human brain tissue
Scientific Data· 2024DOI
Alex Olar, Teodora Tyler, Paulina Hoppa, Erzsébet Frank, István Csabai, István Adriján, Péter Pollner
CCSW 2024 -- Cloud Computing Security Workshop
Proceedings of the 2024 on ACM SIGSAC Conference on Computer and Communications Security· 2024DOI
Apostolos Fournaris, Paolo Palmieri
ExaFlexHH: an exascale-ready, flexible multi-FPGA library for biologically plausible brain simulations
Frontiers in Neuroinformatics· 2024DOI
Rene Miedema; Christos Strydis
HealthMesh: An Architectural Framework for Federated Healthcare Data Management
Proceedings of the 26th International Workshop on Design, Optimization, Languages and Analytical Processing of Big Data (DOLAP 2024)· 2024
Aniol Bisquert, Achraf Hmimou, Josep Ll. Berral, Alberto Gutierrez-Torre, Oscar Romero
Learning using privileged information for segmenting tumors on digital mammograms
CoRR· 2024DOI
Ioannis N. Tzortzis; Konstantinos Makantasis; Ioannis Rallis; Nikolaos Bakalos; Anastasios Doulamis; Nikolaos Doulamis
Memristor-Based Lightweight Encryption
26th Euromicro Conference on Digital System Design· 2024DOI
Siddiqi, Muhammad Ali, Jan Andrés Galvan Hernández, Anteneh Gebregiorgis, Rajendra Bishnoi, Christos Strydis, Said Hamdioui, and Mottaqiallah Taouil, 2023.
NeuroDots: From Single-Target to Brain-
Neuromodulation: Technology at the Neural Interface· 2024DOI
Dirk De Ridder, Muhammad Ali Siddiqi, Justin Dauwels, Wouter A. Serdijn, Christos Strydis
SECURED for Health: Scaling Up Privacy to Enable the Integration of the European Health Data Space
2024 Design, Automation & Test in Europe Conference & Exhibition (DATE)· 2024DOI
Francesco Regazzoni, Paolo Palmieri, George Tasopoulos, et al
SECURED: Project updates and legal insights for the beginning of its second year (Part I)
CiTiP Blog· 2024
Maja Nisevic, Daniela Spajic
SECURED: Project updates and legal insights for the beginning of its second year (Part II)
CiTiP Blog· 2024
Maja Nisevic, Daniela Spajic
Tricking AI chips into simulating the human brain: A detailed performance analysis
Neurocomputing· 2024DOI
Landsmeer, Lennart P.L.; Engelen, Max C.W.; Miedema, Rene; Strydis, Christos
Tricking AI chips into Simulating the Human Brain: A Detailed Performance Analysis
Neurocomputing· 2024DOI
Lennart P. L. Landsmeer, Max C. W. Engelen, Rene Miedema, Christos Strydis,
A Multithread AES Accelerator for Cyber-Physical Systems
CF '23: Proceedings of the 20th ACM International Conference on Computing Frontiers· 2023DOI
Francesco Ratto, Luigi Raffo and Francesca Palumbo
Anonymous vs. pseudonymous data: the CJEU reaffirms the relative approach to the concept of personal data
CiTiP Blog· 2023
Daniela Spajic
Beyond Parameter Averaging in Model Aggregation
International Workshop on Federated Learning in the Age of Foundation Models in Conjunction with NeurIPS 2023· 2023
Pol G Recasens, Jordi Torres, Josep Berral, Søren Hauberg, Pablo Moreno-Muñoz
Client-specific Property Inference against Secure Aggregation in Federated Learning
WPES '23: Proceedings of the 22nd Workshop on Privacy in the Electronic Society· 2023DOI
Raouf Kerkouche, Gergely Acs, Mario Fritz
Dilithium Hardware-Accelerated Application Using OpenCL-Based High-Level Synthesis
2023 IEEE/ACM International Conference on Computer Aided Design (ICCAD)· 2023DOI
Alexander Islam El-Kady, Apostolos P. Fournaris, Vassilis Paliuras
Towards Accelerating the Adoption of Federated Learning for Heterogeneous Data
PETRA '23: Proceedings of the 16th International Conference on PErvasive Technologies Related to Assistive Environments· 2023DOI
Christos Ntokos; Nikolaos Bakalos; Dimitrios Kalogeras
Treating a different kind of patient: curing security weaknesses in digital health systems of the future
· 2023DOI
Francesco Regazzoni; Paolo Palmieri; Apostolos P Fournaris
Deliverables (10)
Other Results (1)
Periodic Reporting for period 1 - SECURED (Scaling Up secure Processing, Anonymization and generation of Health Data for EU cross border collaborative research and Innovation)