Systemic approaches to improve cardiometabolic and brain health during lifespan

MSCA (Marie Skłodowska-Curie)HORIZON-TMA-MSCA-Cofund-PID: 101126611
EC Contribution
€31,522
Consortium Size
5 orgs
Start Year
2023
▶Summary

Systemic approaches to improve cardiometabolic and brain health during lifespan (SYS-LIFE) is an exciting new postdoctoral fellowship programme that seeks to deliver urgently-needed breakthroughs in the field of cardiometabolic and brain diseases (e.g. heart attacks, strokes, depression and diabetes), promote scientific renewal in this field and develop its future leaders of tomorrow. It is based at the University of Turku (UTU) in Finland and supported by partners in different sectors. UTU’s Collegia have a record for excellence in research and for developing their researchers for leadership roles. SYS-LIFE applies their bottom-up, 'Institute for Advanced Study' model to build on UTU’s outstanding expertise and unique facilities for cardiometabolic and brain health research. It will recruit 11 experienced postdoctoral researchers (ERs) in 2023 and 2024 (22 in total), each for 36 months, through an open, international, competitive, merit-based selection process dependent on external peer-review, in line with the European Charter and Code. Projects that are interdisciplinary, intersectoral, longitudinal or systemic are encouraged. At UTU, such approaches have resulted in major advances in cardiometabolic and brain health. SYS-LIFE offers • Scientific excellence: Fellows will be free to design and pursue novel, high-quality research projects that seek to improve health outcomes in this area, connecting and strengthening research and resources at UTU and beyond; • Career development: SYS-LIFE offers mentoring and a new range of options for non-tenured researchers to develop as future leaders, enabling them to move freely between sectors to acquire unique skills and experiences; • Innovation: SYS-LIFE (i) enables knowledge and technology to circulate freely at regional, national and international levels, (ii) connects intellectual excellence with the practical know-how and infrastructure needed to realise new concepts; (iii) offers dedicated Proof-of-Concept funds.

Consortium (5)

🇫🇮 TURUN YLIOPISTOFI
coordinator
🇫🇮 BUSINESS TURKU OY ABFI
partner
🇩🇪 SIEMENS HEALTHCARE GMBHDE
partner
🇧🇪 UNIVERSITEIT GENTBE
partner
🇫🇮 VARSINAIS-SUOMEN SAIRAANHOITOPIIRIN KUNTAYHTYMAFI
partner

Project Results (13)

Source: CORDIS, the EU research results database.

▶Publications (10)
Coronary atherosclerosis on AI-based plaque analysis in patients with chest pain and calcium score zero
The International Journal of Cardiovascular Imaging· 2026DOI
David Molnar, Juhani Knuuti, Jeroen J. Bax, Antti Saraste, Teemu Maaniitty
Ameliorative effect of Hibiscus sabdariffa leaf flavonoid extract on the PSA/CEA/AKT/MMP-9 signaling pathway in benign prostatic hyperplasia-induced rats
Comparative Clinical Pathology· 2025DOI
Basiru Olaitan Ajiboye, Courage Dele Famusiwa, Efekemo Emmanuel Oghenemine, Agboola Deborah Imoleyemi, Olapade Samuel Akinlolu, Toluwase Hezekiah Fatoki, Abigail Omotayo Agbolade, Adetutu Omolola Ojelabi, Olawale Razaq Ajuwon, Babatunji Emmanuel Oyinloye, Marcello Iriti, Mary Abiola Okesola, Oluwafemi Adeleke Ojo
Associations between gut microbiome and circulating cytokines: a cross-sectional analysis in the FINRISK 2002 population cohort
Gut Pathogens· 2025DOI
Diab, Hassan; Langen, Ville; Yeo, Li-Fang; Salomaa, Veikko; Havulinna, Aki; Lahti, Leo; Pärnänen, Katariina; Knight, Rob; Jalkanen, Sirpa; Salmi, Marko; Niiranen, Teemu; Palmu, Joonatan
Exploring high dental anxiety subtypes using cluster analysis approach: a cross-sectional study
BMC Oral Health· 2025DOI
Mika Kajita, Vesa Pohjola, Eeva-Leena Kataja, Satu Lahti
Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies
Food Safety and Health· 2025DOI
Gideon Ampoma Gyebi, Damilare Emmanuel Rotimi, Moyosoreoluwa Oduba, Ifeoma Nnonyelu, Matthew Iyobhebhe, Musiliyu Ayofe Salawu, Adebola Busola Ojo, Odunayo Anthonia Taiwo, Adesoji Alani Olanrewaju, Abel Kolawole Oyebamiji, Mubarak Alruwaili, Naif H. Ali, Saud A. Alnaaim, Bshra A. Alsfouk, Gaber El‐Saber Batiha, Oluwafemi Adeleke Ojo
Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential
Therapeutic Delivery· 2025DOI
Sharon Oladipupo, Damilare Emmanuel Rotimi, Emmanuel Henry Ezenabor, Adebola Busola Ojo, Oluwatomisin Aderonke Akinsola, Oluwafemi Adeleke Ojo
MSS-PAE: Saving Autoencoder-based Outlier Detection from Unexpected Reconstruction
Pattern Recognition· 2025DOI
Xu Tan, Jiawei Yang, Junqi Chen, Sylwan Rahardja, Susanto Rahardja
Sex differences in plaque burden and outcomes in symptomatic patients with suspected coronary artery disease
International Journal of Cardiology· 2025DOI
David Molnar, Juhani Knuuti, Jeroen J. Bax, Antti Saraste, Teemu Maaniitty
The Impact of Maternal Supplementation of Fish Oil and/or Probiotics During Pregnancy on the Serum Metabolomic Profile From Infancy to Childhood: Secondary Analysis of a Randomized Placebo-Controlled Trial
Current Developments in Nutrition· 2025DOI
Veera Houttu, Dattatray Mongad, Noora Houttu, Lotta Saros, Chunpeng Zhang, Jenni Viitaharju, Tero Vahlberg, Leo Lahti, Kirsi Laitinen
The UPR-oxidative stress nexus in diabetes and obesity: Exploring innovative therapeutic approaches for metabolic control
Obesity Medicine· 2025DOI
Clinton Ayodeji Akanbi, Oluwafemi Adeleke Ojo
▶Deliverables (2)
Call 1: Link to Euraxess website
Other
Call 2: Link to Euraxess website
Other
▶Other Results (1)
Periodic Reporting for period 1 - SYS-LIFE (Systemic approaches to improve cardiometabolic and brain health during lifespan)